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physics.bio-ph2024
The Interplay of Heterogeneity and Product Detachment in Templated Polymer Copying
Jeremy E. B. Guntoro, Benjamin J. Qureshi, Thomas E. Ouldridge
Templated copolymerization, in which information stored in the sequence of a heteropolymer template is copied into another polymer product, is the mechanism behind all known method…
physics.bio-ph2024★ 2 cited
Thermodynamic limits on general far-from-equilibrium molecular templating networks
Benjamin Qureshi, Jenny M. Poulton, Thomas E. Ouldridge
Cells produce RNA and proteins via molecular templating networks. We show that information transmission in such networks is bounded by functions of a simple thermodynamic property…