3 papers
q-bio.GN2026
Screening of Biosecurity Features in Metagenomic Data with Evo 2 Probes
Jeremy Guntoro, Alexander Dack, Dylan Danno +3
Genomic foundation models such as Evo 2 learn rich sequence representations, but their value for biosecurity screening is largely unexplored. We ask how much biosecurity-relevant s…
physics.bio-ph2024
The Interplay of Heterogeneity and Product Detachment in Templated Polymer Copying
Jeremy E. B. Guntoro, Benjamin J. Qureshi, Thomas E. Ouldridge
Templated copolymerization, in which information stored in the sequence of a heteropolymer template is copied into another polymer product, is the mechanism behind all known method…
physics.bio-ph2024
The Role of Sequence Information in Minimal Models of Molecular Assembly
Jeremy Guntoro, Thomas Ouldridge
Sequence-directed assembly processes - such as protein folding - allow the assembly of a large number of structures with high accuracy from only a small handful of fundamental buil…