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physics.med-ph2025

A recent evaluation on the performance of LLMs on radiation oncology physics using questions of randomly shuffled options

Peilong Wang, Jason Holmes, Zhengliang Liu +4

Purpose: We present an updated study evaluating the performance of large language models (LLMs) in answering radiation oncology physics questions, focusing on the recently released…

physics.med-ph2025

Diffusion Transformer-based Universal Dose Denoising for Pencil Beam Scanning Proton Therapy

Yuzhen Ding, Jason Holmes, Hongying Feng +13

Purpose: Intensity-modulated proton therapy (IMPT) offers precise tumor coverage while sparing organs at risk (OARs) in head and neck (H&N) cancer. However, its sensitivity to anat…

physics.med-ph2025

Critical review of patient outcome study in head and neck cancer radiotherapy

Jingyuan Chen, Yunze Yang, Chenbin Liu +8

Rapid technological advances in radiation therapy have significantly improved dose delivery and tumor control for head and neck cancers. However, treatment-related toxicities cause…

physics.med-ph2025

Fine-Tuning Open-Source Large Language Models to Improve Their Performance on Radiation Oncology Tasks: A Feasibility Study to Investigate Their Potential Clinical Applications in Radiation Oncology

Peilong Wang, Zhengliang Liu, Yiwei Li +12

Background: The radiation oncology clinical practice involves many steps relying on the dynamic interplay of abundant text data. Large language models have displayed remarkable cap…

physics.med-ph2025

Evaluating The Performance of Using Large Language Models to Automate Summarization of CT Simulation Orders in Radiation Oncology

Meiyun Cao, Shaw Hu, Jason Sharp +10

Purpose: This study aims to use a large language model (LLM) to automate the generation of summaries from the CT simulation orders and evaluate its performance. Materials and Metho…

physics.med-ph2024

Enabling Clinical Use of Linear Energy Transfer in Proton Therapy for Head and Neck Cancer -- A Review of Implications for Treatment Planning and Adverse Events Study

Jingyuan Chen, Yunze Yang, Hongying Feng +12

Proton therapy offers significant advantages due to its unique physical and biological properties, particularly the Bragg peak, enabling precise dose delivery to tumors while spari…