735 citations · 1.9k across the 14 of their papers we have counts for
5 papers · 1 filter
From Physics to Statistics: A Simple Route to Exponential Families via Maximum Entropy
Korbinian Strimmer
Exponential families form the backbone of modern statistics and machine learning, but textbooks seldom derive them from first principles in an accessible way. Although minimal suff…
A whitening approach to probabilistic canonical correlation analysis for omics data integration
Takoua Jendoubi, Korbinian Strimmer
Background: Canonical correlation analysis (CCA) is a classic statistical tool for investigating complex multivariate data. Correspondingly, it has found many diverse applications,…
Optimal whitening and decorrelation
Agnan Kessy, Alex Lewin, Korbinian Strimmer
Whitening, or sphering, is a common preprocessing step in statistical analysis to transform random variables to orthogonality. However, due to rotational freedom there are infinite…
Signal Identification for Rare and Weak Features: Higher Criticism or False Discovery Rates?
Bernd Klaus, Korbinian Strimmer
Signal identification in large-dimensional settings is a challenging problem in biostatistics. Recently, the method of higher criticism (HC) was shown to be an effective means for…
Learning false discovery rates by fitting sigmoidal threshold functions
Bernd Klaus, Korbinian Strimmer
False discovery rates (FDR) are typically estimated from a mixture of a null and an alternative distribution. Here, we study a complementary approach proposed by Rice and Spiegelha…