3 papers
econ.EM2026
A framework for assessing value and heterogeneity, illustrated using an early model of population screening with a multi-cancer early detection test
N Kunst, S Dias, K Payne +2
Introduction: We present a framework to assess the economic value of healthcare interventions by disaggregating value and examining heterogeneity. We applied it to an early health-…
stat.ME2026
Modelling multi-cancer screening data to infer on natural history of disease: when can valid, identifiable and precise inference be obtained?
MO Soares, J Lange, K Gogebakan +5
Background: Multistate models (MSMs) applied to screening data can characterise the natural history of cancer and predict "stage-shifts" from screening. However, inferring paramete…
stat.ME2025
Modelling the impact of Multi Cancer Early Detection tests: a review of natural history of disease models
O Mandrik, S Whyte, N Kunst +6
Introduction: The potential for multi-cancer early detection (MCED) tests to detect cancer at earlier stages is currently being evaluated in screening clinical trials. Once trial e…