38 citations · 58 across the 7 of their papers we have counts for
7 papers
Liquid-liquid phase separation precedes crystallization in supercooled water-glycerol solutions
Iason Andronis, Sharon Berkowicz, Mariia Filianina +10
Understanding the structural evolution of supercooled water-glycerol solutions is important for cryopreservation, yet distinguishing liquid-state transformations from ice crystalli…
Nanoscale Protein Diffusion in Supercooled Cryoprotectant Solutions
Maddalena Bin, Anita Girelli, Mariia Filianina +15
Vitrification during cryopreservation requires a quantitative understanding of protein transport in deeply supercooled cryoprotectant solutions, yet direct measurements at molecula…
Supercritical density fluctuations and structural heterogeneity in supercooled water-glycerol microdroplets
Sharon Berkowicz, Iason Andronis, Anita Girelli +9
Recent experiments and theoretical studies strongly indicate that water exhibits a liquid-liquid phase transition (LLPT) in the supercooled domain. An open question is how the LLPT…
Coherent X-rays reveal anomalous molecular diffusion and cage effects in crowded protein solutions
Anita Girelli, Maddalena Bin, Mariia Filianina +38
Understanding protein motion within the cell is crucial for predicting reaction rates and macromolecular transport in the cytoplasm. A key question is how crowded environments affe…
Nanocrystallites Modulate Intermolecular Interactions in Cryoprotected Protein Solutions
Mariia Filianina, Maddalena Bin, Sharon Berkowicz +7
Studying protein interactions at low temperatures has important implications for optimizing cryostorage processes of biological tissue, food, and protein-based drugs. One of the ma…
Coherent X-ray Scattering Reveals Nanoscale Fluctuations in Hydrated Proteins
Maddalena Bin, Mario Reiser, Mariia Filianina +15
Hydrated proteins undergo a transition in the deeply supercooled regime, which is attributed to rapid changes in hydration water and protein structural dynamics. Here, we investiga…
Resolving molecular diffusion and aggregation of antibody proteins with megahertz X-ray free-electron laser pulses
Mario Reiser, Anita Girelli, Anastasia Ragulskaya +26
X-ray free-electron lasers (XFELs) with megahertz repetition rate can provide novel insights into structural dynamics of biological macromolecule solutions. However, very high dose…