5 papers
Exchange and Microviscosity of Dynamic Nanocompartments
Romana Shathy, Alexandria Guinness, John M Franck
RMs (reverse micelles) provide a controlled system for studying the unique structural and dynamic behaviors of confined water, thus gaining a general insight into the behavior or w…
Separate and Detailed Treatment of Absolute Signal and Noise Enables NMR Under Adverse Circumstances
A Guinness, AA Beaton, JM Franck
When deploying a spectrometer in an adverse environment, such as during a typical ODNP experiment or experiments that require low-volume low-field measurements, a clear and modern…
Contiguous Patches of Translational Hydration Dynamics on the Surface of K-Ras
Farhana Syed, Jessica N. Khuc, Alexandria Guinness +1
Proteins involved in signaling pathways represent an interesting target for experimental analysis by ODNP (Overhauser Dynamic Nuclear Polarization), which determines the translatio…
Rapidly Screening the Correlation Between the Rotational Mobility and the Hydrogen Bonding Strength of Confined Water
Alec A. Beaton, Alexandria Guinness, John M. Franck
Past research has conclusively shown that confined pockets of water exhibit properties that differ from those of unconfined ("bulk") water. The differences between confined water a…
A Modernized View of Coherence Pathways Applied to Magnetic Resonance Experiments in Unstable, Inhomogeneous Fields
Alec A. Beaton, Alexandria Guinness, John M. Franck
Over recent decades, the value of conducting experiments at lower frequencies and in inhomogeneous and/or time-variable fields has grown. For example, an interest in the nanoscale…