46 citations · 142 across the 8 of their papers we have counts for
8 papers
Facile One Pot Synthesis of Hybrid Core-Shell Silica-Based Sensors for Live Imaging of Dissolved Oxygen and Hypoxia Mapping in 3D cell models
Helena Iuele, Stefania Forciniti, Valentina Onesto +6
Fluorescence imaging allows for non-invasively visualizing and measuring key physiological parameters like pH and dissolved oxygen. In our work, we created two ratiometric fluoresc…
A Fluorescent Ratiometric Potassium Sensor Based on IPG4-Silica Microparticles for Selective Detection and Fluorescence Imaging of Potassium Cations
Francesco Colella, Stefania Forciniti, Valentina Onesto +4
Potassium cations play many important roles in living organisms, especially in electro-physiology, since they are involved in neurotransmission and muscle contractions. We report t…
A 3D Pancreatic Cancer Model with Integrated Optical Sensors for Noninvasive Metabolism Monitoring and Drug Screening
Anna Chiara Siciliano, Stefania Forciniti, Valentina Onesto +6
A distinct feature of pancreatic ductal adenocarcinoma (PDAC) is a prominent tumor microenvironment (TME) with remarkable cellular and spatial heterogeneity that meaningfully impac…
Highly Sensitive Ratiometric Fluorescent Fiber Matrixes for Oxygen Sensing with Micrometer-Spatial Resolution
Giuliana Grasso, Valentina Onesto, Stefania Forciniti +8
Oxygen (O2)-sensing matrices are promising tools for the live monitoring of extracellular O2 consumption levels in long-term cell cultures. In this study, ratiometric O2-sensing me…
Metabolic coordination and phase transitions in spatially distributed multi-cellular systems
Krishnadev Narayanankutty, José Antonio Pereiro-Morejon, Arián Ferrero-Fernández +7
During overflow metabolism, cells excrete glycolytic byproducts when growing under aerobic conditions in a seemingly wasteful fashion. While potentially advantageous for microbes w…
A pH Sensor Scaffold for Mapping Spatiotemporal Gradients in Three Dimensional In Vitro Tumour Models
Riccardo Rizzo, Valentina Onesto, Stefania Forciniti +6
The detection of extracellular pH at single cell resolution is challenging and requires advanced sensibility. Sensing pH at a high spatial and temporal resolution might provide cru…
Fluorescent nano- and microparticles for sensing cellular microenvironment: past, present and future applications
Giuliana Grasso, Francesco Colella, Stefania Forciniti +7
The tumor microenvironment (TME) features distinct hallmarks, including acidosis, hypoxia, reactive oxygen species (ROS) generation, and altered ion fluxes, which are crucial targe…
NIR ICG-Enhanced Fluorescence: A Quantitative Evaluation of Bowel Microperfusion and Its Relation to Central Perfusion in Colorectal Surgery
N. Depalma, S. D Ugo, F. Manoochehri +10
Background: To date, no standardized protocols nor a quantitative assessment of the near-infrared fluorescence angiography with indocyanine green (NIR-ICG) are available. The aim o…