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cs.CE2026
LineageFlow: Flow Matching for High-Fidelity Family-Aware Protein Sequence Generation
Langzhang Liang, Ming Yang, Yi Feng +6
Protein sequence generation for engineering requires samples that are biophysically plausible and, when targeting a family/domain, remain recognizable members while exploring withi…
cs.LG2026
DARC: Disagreement-Aware Alignment via Risk-Constrained Decoding
Mingxi Zou, Jiaxiang Chen, Junfan Li +4
Preference-based alignment methods (e.g., RLHF, DPO) typically optimize a single scalar objective, implicitly averaging over heterogeneous human preferences. In practice, systemati…