7 citations · 14 across the 5 of their papers we have counts for
5 papers
Oxygenation and spatial heterogeneity shape radiotherapy protocol ranking through phenotypic adaptation
Francesco Albanese, Giulia Chiari, Marcello Edoardo Delitala
Tumor response to radiotherapy is strongly influenced by oxygen availability and phenotypic heterogeneity, yet their combined impact on the relative performance of fractionation sc…
A phenotype-structured mathematical model for the influence of hypoxia on oncolytic virotherapy
David Morselli, Giulia Chiari, Federico Frascoli +1
The effectiveness of oncolytic virotherapy is significantly affected by several elements of the tumour microenvironment, which reduce the ability of the virus to infect cancer cell…
Multi-scale modeling of Snail-mediated response to hypoxia in tumor progression
Giulia Chiari, Martina Conte, Marcello Delitala
Tumor cell migration within the microenvironment is a crucial aspect for cancer progression and, in this context, hypoxia has a significant role. An inadequate oxygen supply acts a…
Hypoxia-related radiotherapy resistance in tumours: treatment efficacy investigation in an eco-evolutionary perspective
Giulia Chiari, Giada Fiandaca, Marcello Edoardo Delitala
In the study of therapeutic strategies for the treatment of cancer, eco-evolutionary dynamics are of particular interest, since characteristics of the tumour population, interactio…
Hypoxia-resistance heterogeneity in tumours: the impact of geometrical characterization of environmental niches and evolutionary trade-offs. A mathematical approach
Giulia Chiari, Giada Fiandaca, Marcello Edoardo Delitala
In the study of cancer evolution and therapeutic strategies, scientific evidence shows that a key dynamics lies in the tumor-environment interaction. In particular, oxygen concentr…