398 citations · 983 across the 13 of their papers we have counts for
13 papers
SmartTrap: Automated Precision Experiments with Optical Tweezers
Martin Selin, Antonio Ciarlo, Giuseppe Pesce +10
There is a trend in research towards more automation using smart systems powered by artificial intelligence. While experiments are often challenging to automate, they can greatly b…
DNA Calorimetric Force Spectroscopy at Single Base Pair Resolution
Paolo Rissone, Marc Rico-Pasto, Steve Smith +1
DNA hybridization is a fundamental reaction with wide-ranging applications in biotechnology. The nearest-neighbor (NN) model provides the most reliable description of the energetic…
Nonequilibrium work relations for energy and information
Felix Ritort
I review basic concepts in the nonequilibrium physics of small systems, emphasizing single molecule experiments and how they contribute to expanding our current understanding of en…
Universal Cold RNA Phase Transitions
Paolo Rissone, Aurelien Severino, Isabel Pastor +1
RNA's diversity of structures and functions impacts all life forms since primordia. We use calorimetric force spectroscopy to investigate RNA folding landscapes in previously unexp…
Efficient methods for determining folding free energies in single-molecule pulling experiments
Aurelien Severino, Alvaro Martinez Monge, Paolo Rissone +1
The remarkable accuracy and versatility of single-molecule techniques make possible new measurements that are not feasible in bulk assays. Among these, the precise estimation of fo…
Non-specific binding of Na and Mg to RNA determined by force spectroscopy methods
C. V. Bizarro, A. Alemany, F. Ritort
RNA duplex stability depends strongly on ionic conditions, and inside cells RNAs are exposed to both monovalent and multivalent ions. Despite recent advances, we do not have genera…