56 citations · 83 across the 6 of their papers we have counts for
4 papers · 1 filter
Active Hydrodynamic Theory of Euchromatin and Heterochromatin
S. Alex Rautu, Alexandra Zidovska, David Saintillan +1
The genome contains genetic information essential for cell's life. The genome's spatial organization inside the cell nucleus is critical for its proper function including gene regu…
Conformations, correlations, and instabilities of a flexible fiber in an active fluid
Scott Weady, David B. Stein, Alexandra Zidovska +1
Fluid-structure interactions between active and passive components are important for many biological systems to function. A particular example is chromatin in the cell nucleus, whe…
Activity-driven phase transition causes coherent flows of chromatin
Iraj Eshghi, Alexanda Zidovska, Alexander Y. Grosberg
We discover a new type of nonequilibrium phase transition in a model of chromatin dynamics, which accounts for the coherent motions that have been observed in experiment. The coher…
Model chromatin flows: numerical analysis of linear and nonlinear hydrodynamics inside a sphere
Iraj Eshghi, Alexandra Zidovska, Alexander Y. Grosberg
We solve a hydrodynamic model of active chromatin dynamics, within a confined geometry simulating the cell nucleus. Using both analytical and numerical methods, we describe the beh…