4 papers
Multivariate Augmented Prediction-Powered Survival Inference for EHR Association Studies With Limited Chart Review
Xicheng Xie, Katherine Fiona Simpson, Hyojung Jang +2
Objective: To reduce bias and improve precision in survival association studies using electronic health record (EHR) data when computational phenotypes (CPs) for outcomes and covar…
Studying Competing Events with Federated Cumulative Incidence Curves
Malcolm Risk, Shuang Yang, Jiang Bian +6
Combining electronic health record (EHR) data from multiple institutions is a valuable strategy for conducting post-market safety surveillance of medical products, but privacy conc…
Privacy-preserving causal mediation analysis using distributed electronic health record networks
Hyojung Jang, Rotana Radwan, Malcolm Risk +5
Electronic health record (EHR) networks provide unprecedented opportunities to study treatment mechanisms at scale, but mediation analyses across institutions are often hindered by…
Time-to-Event Modeling with Pseudo-Observations in Federated Settings
Hyojung Jang, Malcolm Risk, Yaojie Wang +3
In multi-center clinical research, privacy regulations often prohibit pooling individual-level records, complicating the analysis of time-to-event data. Current federated survival…