513 citations · 1k across the 21 of their papers we have counts for
3 papers · 1 filter
Crowding effects on the structural transitions in a flexible helical homopolymer
Alexander Kudlay, Margaret S. Cheung, D. Thirumalai
We elucidate the structural transitions in a helical off-lattice homopolymer induced by crowding agents, as function of the number of monomers () and volume fraction () of…
Protein folding mediated by solvation: water expelling and formation of the hydrophobic core occurs after the structure collapse
Margaret S. Cheung, Angel E. Garcia, Jose N. Onuchic
The interplay between structure-search of the native structure and desolvation in protein folding has been explored using a minimalist model. These results support a folding mechan…
Mechanisms underlying sequence-independent beta-sheet formation
Chinlin Guo, Herbert Levine, Margaret S. Cheung +1
We investigate the formation of beta-sheet structures in proteins without taking into account specific sequence-dependent hydrophobic interactions. To accomplish this, we introduce…