4 papers
LLM-based Agents for Forecasting and Prediction: Methods, Training, Evaluation, and Applications
Xiaogang Xu, Jiaqi Tang, Jianmin Chen +12
Large language models (LLMs) now support forecasting systems that combine language-based reasoning with temporal data, evidence retrieval, external tools, and iterative prediction.…
PertMind: Eliciting Emergent Biological Reasoning in LLM via Reinforcement Learning on Cellular Perturbation Data
Zhenchao Tang, Xiaogang Xu, Tianxu Lv +8
Large language models can describe mechanisms, yet scalable post-training still depends on costly, manually curated biological reasoning traces. Here we show that cellular perturba…
Branch-JEPA: Finite-Support Predictive Distributions for JEPA World Models
Zhi Song, Ximing Xing, Zhenchao Tang +9
Joint-embedding predictive architectures (JEPAs) learn dynamics by predicting future observations in representation space. Yet most JEPA world models return one latent successor, e…
Aligning LLMs with Biomedical Knowledge using Balanced Fine-Tuning
Zhenchao Tang, Fang Wang, Haohuai He +12
Engineering LLMs to accelerate life sciences research requires a robust alignment with biomedical knowledge. We observe that biomedical text exhibits a fundamentally different unce…