3 papers
stat.ME2026
Causally-interpretable meta-analysis using aggregate data
Qingyang Shi, Wouter van Amsterdam, Sacha la Bastide-van Gemert +2
Evidence syntheses and meta-analyses are used to inform clinical practice guidelines and health economic evaluations. However, heterogeneity of treatment effects poses a significan…
stat.ME2026
Causal Meta-Analysis: Rethinking the Foundations of Evidence-Based Medicine
Clément Berenfeld, Ahmed Boughdiri, Bénédicte Colnet +5
Meta-analysis, by synthesizing effect estimates from multiple studies conducted in diverse settings, stands at the top of the evidence hierarchy in clinical research. Yet, conventi…
stat.ME2025
A causal viewpoint on prediction model performance under changes in case-mix: discrimination and calibration respond differently for prognosis and diagnosis predictions
Wouter A. C. van Amsterdam
Prediction models need reliable predictive performance as they inform clinical decisions, aiding in diagnosis, prognosis, and treatment planning. The predictive performance of thes…