3 papers
stat.ME2026
Implementing the principal stratum strategy for intercurrent events with survival outcomes: a tutorial
Xiaoxiao Zhou, Joyce Chen, Pallavi Mishra-Kalyani +5
The International Council for Harmonization (ICH) E9 (R1) addendum provides the estimand framework to formulate treatment effects in a clinical trial. One of the attributes of an e…
stat.ME2026
Two-stage Least Squares with Clustered Data under the Local Average Treatment Effect Framework
Anqi Zhao, Peng Ding, Fan Li
To estimate the causal effect of an endogenous treatment using clustered data, the canonical two-stage least squares (2sls) estimates a linear regression of the outcome on treatmen…
stat.ME2026
Two-stage least squares with treatment-covariate interactions for treatment effect heterogeneity
Anqi Zhao, Peng Ding, Fan Li
Treatment effect heterogeneity with respect to covariates is common in instrumental variable (IV) analyses. An intuitive approach, which we call the interacted two-stage least squa…