137 citations · 1.6k across the 45 of their papers we have counts for
46 papers
Optimal control applied to viral competition
Javier López-Pedrares, Cristiana J. Silva, M. Elena Vázquez-Cendón +1
The emergence of mutant lineages within a viral species has become a public health problem, as the existing treatments and drugs are usually more effective on the original lineages…
Optimal Control of Microcephaly Under Vertical Transmission of Zika
Dilara Yapışkan, Cristiana J. Silva, Delfim F. M. Torres
The Zika virus, known for its potential to induce neurological conditions such as microcephaly when transmitted vertically from infected mothers to infants, has sparked widespread…
An Analytic Method to Determine the Optimal Time for the Induction Phase of Anesthesia
Mohamed A. Zaitri, Cristiana J. Silva, Delfim F. M. Torres
We obtain an analytical solution for the time-optimal control problem in the induction phase of anesthesia. Our solution is shown to align numerically with the results obtained fro…
Stability Analysis of Delayed COVID-19 Models
Mohamed A. Zaitri, Cristiana J. Silva, Delfim F. M. Torres
We analyze mathematical models for COVID-19 with discrete time delays and vaccination. Sufficient conditions for the local stability of the endemic and disease-free equilibrium poi…
A SIQRB delayed model for cholera and optimal control treatment
Ana P. Lemos-Paiao, Helmut Maurer, Cristiana J. Silva +1
We improve a recent mathematical model for cholera by adding a time delay that represents the time between the instant at which an individual becomes infected and the instant at wh…
Model-free based control of a HIV/AIDS prevention model
Loïc Michel, Cristiana J. Silva, Delfim F. M. Torres
Controlling an epidemiological model is often performed using optimal control theory techniques for which the solution depends on the equations of the control system, objective fun…