4 papers
Robust Moment-Based Estimation via Spectral Gradient Reweighting
Liu Zhang, Amit Singer
Moment-based estimation is a theoretically attractive approach to parametric inference, especially when likelihood-based estimation is unavailable, misspecified, or computationally…
Bayesian Perspective for Orientation Determination in Cryo-EM with Application to Structural Heterogeneity Analysis
Sheng Xu, Amnon Balanov, Amit Singer +1
Accurate orientation estimation is a crucial component of 3D molecular structure reconstruction, both in single-particle cryo-electron microscopy (cryo-EM) and in the increasingly…
Subspace method of moments for ab initio 3-D single-particle cryo-EM reconstruction
Jeremy Hoskins, Yuehaw Khoo, Oscar Mickelin +2
Cryo-electron microscopy (cryo-EM) is a widely used technique for recovering the 3-D structure of biological molecules from a large number of experimentally generated noisy 2-D tom…
Diagonally-Weighted Generalized Method of Moments Estimation for Gaussian Mixture Modeling
Liu Zhang, Oscar Mickelin, Sheng Xu +1
Since Pearson [Philosophical Transactions of the Royal Society of London. A, 185 (1894), pp. 71-110] first applied the method of moments (MM) for modeling data as a mixture of one-…