2 papers
stat.ME2026
Efficient and Debiased Learning of Average Hazard Under Non-Proportional Hazards
Xiang Meng, Lu Tian, Kenneth Kehl +1
The hazard ratio from the Cox proportional hazards model is a ubiquitous summary of treatment effect. However, when hazards are non-proportional, the hazard ratio can lose a stable…
stat.ME2024
Assessing Delayed Treatment Benefits of Immunotherapy Using Long-Term Average Hazard: A Novel Test/Estimation Approach
Miki Horiguchi, Lu Tian, Kenneth L. Kehl +1
Delayed treatment effects on time-to-event outcomes have often been observed in randomized controlled studies of cancer immunotherapies. In the case of delayed onset of treatment e…