2 papers
q-bio.NC2026
Energy budgets govern synaptic precision and its regulation during plasticity
James Malkin, Cian O'Donnell, Conor Houghton
Synaptic transmission must balance the need for reliable signalling against the metabolic cost of achieving that reliability. How energetic constraints shape synaptic precision and…
q-bio.NC2023
Signatures of Bayesian inference emerge from energy efficient synapses
James Malkin, Cian O'Donnell, Conor Houghton +1
Biological synaptic transmission is unreliable, and this unreliability likely degrades neural circuit performance. While there are biophysical mechanisms that can increase reliabil…