2 papers
stat.ME2026
Hybrid Non-informative and Informative Prior Model-assisted Designs for Mid-trial Dose Insertion
Kana Yamada, Hisato Sunami, Kentaro Takeda +2
In oncology phase I trials, model-assisted designs have been increasingly adopted because they enable adaptive yet operationally simple dose adjustment based on accumulating safety…
stat.AP2023
Adjusting confidence intervals under covariate-adaptive randomization in non-inferiority and equivalence trials
Masahiro Kojima, Hirotaka Mano, Kana Yamada +3
Regulatory authorities guide the use of permutation tests or randomization tests so as not to increase the type-I error rate when applying covariate-adaptive randomization in rando…