activity
20092022
most citedAnti-platelet factor 4/polyanion antibodies mediate a new mechanism of autoimmunity

115 citations · 237 across the 8 of their papers we have counts for

collaborators

8 papers

cond-mat.soft2022

Identification and characterization of various plastics using THz-spectroscopy

Tobias Kleinke, Finn-Frederik Stiewe, Tristan Winkel +5

THz spectroscopy has reached imaging capability with a spatial resolution of a few micrometres. This property enables measurements and imaging of biological samples like cells. THz…

physics.bio-ph2020★ 115 cited

Anti-platelet factor 4/polyanion antibodies mediate a new mechanism of autoimmunity

Thi-Huong Nguyen, Nikolay Medvedev, Mihaela Delcea +1

Antibodies recognizing complexes of the chemokine platelet factor 4 (PF4-CXCL4) and polyanions (P) opsonize PF4-coated bacteria hereby mediating bacterial host defense. A subset of…

physics.bio-ph2020★ 50 cited

Rupture Forces among Human Blood Platelets at different Degrees of Activation

Thi-Huong Nguyen, Raghavendra Palankar, Van-Chien Bui +3

Little is known about mechanics underlying the interaction among platelets during activation and aggregation. Although the strength of a blood thrombus has likely major biological…

physics.bio-ph2020★ 11 cited

Drug-induced activation of integrin alpha IIb beta 3 leads to minor localized structural changes

Una Janke, Martin Kulke, Ina Buchholz +3

Integrins are transmembrane proteins involved in hemostasis, wound healing, immunity and cancer. In response to intracellular signals and ligand binding, integrins adopt different…

physics.bio-ph2020★ 19 cited

Interaction of fibrinogen-magnetic nanoparticle bioconjugates with integrin reconstituted into artificial membranes

Ulrike Martens, Una Janke, Sophie Moeller +3

Magnetic nanoparticles have a broad spectrum of biomedical applications including cell separation, diagnostics and therapy. One key issue is little explored: how do the engineered…

physics.bio-ph2020★ 23 cited

Lysine residues control the conformational dynamics of beta 2-glycoprotein I

Ina Buchholz, Peter Nestler, Susan Köppen +1

One of the major problems in the study of the dynamics of proteins is the visualization of changing conformations that are important for processes ranging from enzyme catalysis to…