45 citations · 52 across the 5 of their papers we have counts for
6 papers
pVACtools v6: A comprehensive suite for neoantigen prediction, visualization, and therapy design
My H. Hoang, Susanna Kiwala, Megan Richters +23
With the rise of checkpoint blockade therapies and neoantigen-based vaccines reaching later-stage trials, there is a growing need for computational tools to identify and prioritize…
ImmunoNX: a robust bioinformatics workflow to support personalized neoantigen vaccine trials
Kartik Singhal, Evelyn Schmidt, Susanna Kiwala +36
Personalized neoantigen vaccines represent a promising immunotherapy approach that harnesses tumor-specific antigens to stimulate anti-tumor immune responses. However, the design o…
pVACview: an interactive visualization tool for efficient neoantigen prioritization and selection
Huiming Xia, My Hoang, Evelyn Schmidt +13
Neoantigen targeting therapies including personalized vaccines have shown promise in the treatment of cancers. Accurate identification/prioritization of neoantigens is highly relev…
Bam-readcount -- rapid generation of basepair-resolution sequence metrics
Ajay Khanna, David E. Larson, Sridhar Nonavinkere Srivatsan +10
Bam-readcount is a utility for generating low-level information about sequencing data at specific nucleotide positions. Originally designed to help filter genomic mutation calls, t…
The Cure: Making a game of gene selection for breast cancer survival prediction
Benjamin M. Good, Salvatore Loguercio, Obi L. Griffith +3
Motivation: Molecular signatures for predicting breast cancer prognosis could greatly improve care through personalization of treatment. Computational analyses of genome-wide expre…
KiWi: A Scalable Subspace Clustering Algorithm for Gene Expression Analysis
Obi L. Griffith, Byron J. Gao, Mikhail Bilenky +3
Subspace clustering has gained increasing popularity in the analysis of gene expression data. Among subspace cluster models, the recently introduced order-preserving sub-matrix (OP…