63 citations · 115 across the 4 of their papers we have counts for
4 papers
Influence of Nanoparticle Size and Shape on Oligomer Formation of an Amyloidogenic Peptide
Edward P. O'Brien, John E. Straub, Bernard R. Brooks +1
Understanding the influence of macromolecular crowding and nanoparticles on the formation of in-register -sheets, the primary structural component of amyloid fibrils, is a first…
Theoretical Perspectives on Protein Folding
D. Thirumalai, Edward P. O'Brien, Greg Morrison +1
Understanding how monomeric proteins fold under in vitro conditions is crucial to describing their functions in the cellular context. Significant advances both in theory and experi…
Molecular origin of constant m-values, denatured state collapse, and residue-dependent transition midpoints in globular proteins
Edward P. O'Brien, Bernard R. Brooks, Dave Thirumalai
Experiments show that for many two state folders the free energy of the native state DG_ND([C]) changes linearly as the denaturant concentration [C] is varied. The slope, m = d DG_…
Effect of finite size on cooperativity and rates of protein folding
Maksim Kouza, Mai Suan Li, Edward P. O'Brien +2
We analyze the dependence of cooperativity of the thermal denaturation transition and folding rates of globular proteins on the number of amino acid residues, , using lattice mo…