180 citations · 183 across the 3 of their papers we have counts for
5 papers
Estimation of Interpretable eQTL Effect Sizes Using a Log of Linear Model
John Palowitch, Andrey Shabalin, Yihui Zhou +2
The study of expression Quantitative Trait Loci (eQTL) is an important problem in genomics and biomedicine. While detection (testing) of eQTL associations has been widely studied,…
An Empirical Bayes Approach for Multiple Tissue eQTL Analysis
Gen Li, Andrey A. Shabalin, Ivan Rusyn +2
Expression quantitative trait loci (eQTL) analyses, which identify genetic markers associated with the expression of a gene, are an important tool in the understanding of diseases…
Matrix eQTL: Ultra fast eQTL analysis via large matrix operations
Andrey A. Shabalin
Expression quantitative trait loci (eQTL) mapping aims to determine genomic regions that regulate gene transcription. Expression QTL is used to study the regulatory structure of no…
Reconstruction of a Low-rank Matrix in the Presence of Gaussian Noise
Andrey Shabalin, Andrew Nobel
In this paper we study the problem of reconstruction of a low-rank matrix observed with additive Gaussian noise. First we show that under mild assumptions (about the prior distribu…
Finding large average submatrices in high dimensional data
Andrey A. Shabalin, Victor J. Weigman, Charles M. Perou +1
The search for sample-variable associations is an important problem in the exploratory analysis of high dimensional data. Biclustering methods search for sample-variable associatio…