Showing cs.LGShow all
3 papers · 1 filter
cs.LG2026
Multi-Task Genetic Algorithm with Multi-Granularity Encoding for Protein-Nucleotide Binding Site Prediction
Yiming Gao, Liuyi Xu, Pengshan Cui +3
Accurate identification of protein-nucleotide binding sites is fundamental to deciphering molecular mechanisms and accelerating drug discovery. However, current computational metho…
cs.LG2026
LaPro-DTA: Latent Dual-View Drug Representations and Salient Protein Feature Extraction for Generalizable Drug--Target Affinity Prediction
Zihan Dun, Liuyi Xu, An-Yang Lu +2
Drug--target affinity prediction is pivotal for accelerating drug discovery, yet existing methods suffer from significant performance degradation in realistic cold-start scenarios…
cs.LG2026
Multi-objective Genetic Programming with Multi-view Multi-level Feature for Enhanced Protein Secondary Structure Prediction
Yining Qian, Lijie Su, Meiling Xu +1
Predicting protein secondary structure is essential for understanding protein function and advancing drug discovery. However, the intricate sequence-structure relationship poses si…