Killing of targets by effector CD8${}^{+}$T cells in the mouse spleen follows the law of mass action

Vitaly V. Ganusov, Daniel L. Barber, Rob J. De Boer

It has been difficult to measure efficacy of T cell-based vaccines and to correlate efficacy of CD8${}^{+}$T cell responses with protection against viral infections. In part, this diff…