1.5k citations · 1.5k across the 3 of their papers we have counts for
4 papers
Looking for (Genomic) Needles in a Haystack: Sparsity-Driven Search for Identifying Correlated Genetic Mutations in Cancer
Ritvik Prabhu, Emil Vatai, Bernard Moussad +4
Cancer typically arises not from a single genetic mutation (i.e., hit) but from multi-hit combinations that accumulate within cells. However, enumerating multi-hit combinations bec…
Biophysical comparison of ATP-driven proton pumping mechanisms suggests a kinetic advantage for the rotary process depending on coupling ratio
Ramu Anandakrishnan, Daniel M. Zuckerman
ATP-driven proton pumps, which are critical to the operation of a cell, maintain cytosolic and organellar pH levels within a narrow functional range. These pumps employ two very di…
Building Water Models, A Different Approach
Saeed Izadi, Ramu Anandakrishnan, Alexey V. Onufriev
Simplified, classical models of water are an integral part of atomistic molecular simulations, especially in biology and chemistry where hydration effects are critical. Yet, despit…
Optimal Physical Multipoles
Charles Baker, Ramu Anandakrishnan, Alexey Onufriev
Point multipole expansions are widely used to gain physical insight into complex distributions of charges and to reduce the cost of computing interactions between such distribution…