43 citations · 84 across the 5 of their papers we have counts for
5 papers
Physical and mathematical modeling in experimental papers: achieving robustness of mathematical modeling studies
Vitaly V. Ganusov
Development of several alternative mathematical models for the biological system in question and discrimination between such models using experimental data is the best way to robus…
Mathematical modeling of escape of HIV from cytotoxic T lymphocyte responses
Vitaly V. Ganusov, Richard A. Neher, Alan S. Perelson
Human immunodeficiency virus (HIV-1 or simply HIV) induces a persistent infection, which in the absence of treatment leads to AIDS and death in almost all infected individuals. HIV…
Explicit kinetic heterogeneity: mechanistic models for interpretation of labeling data of heterogeneous cell populations
Vitaly V. Ganusov, Jose Borghans, Rob De Boer
Estimation of division and death rates of lymphocytes in different conditions is vital for quantitative understanding of the immune system. Deuterium, in the form of deuterated glu…
Similar in vivo killing efficacy of polyoma virus-specific CD8 T cells during acute and chronic phases of the infection
Vitaly V. Ganusov, Aron E. Lukacher, Anthony M. Byers
Viral infections can be broadly divided into infections that are cleared from the host (acute) and those that persist (chronic). Why some viruses establish chronic infections while…
Killing of targets by effector CD8T cells in the mouse spleen follows the law of mass action
Vitaly V. Ganusov, Daniel L. Barber, Rob J. De Boer
It has been difficult to measure efficacy of T cell-based vaccines and to correlate efficacy of CD8T cell responses with protection against viral infections. In part, this diff…