most citedExploring the limits of pre-trained embeddings in machine-guided protein design: a case study on predicting AAV vector viability

1 citations · 1 across the 5 of their papers we have counts for

collaborators

5 papers

cs.LG2026

Hakken: Predicting future discoveries to fill the gaps in today's knowledge

Tarek R. Besold, Uchenna Akujuobi, Pablo Sanchez +21

We present Hakken, a domain-agnostic prediction and explanation system performing knowledge prediction, i.e., growing scientific knowledge by establishing novel relationships, ones…

cs.AI2026

Improving Interoperability among Defence and National Security Ontologies: Analysis and Evaluation Tasks

Jonathon Dilworth, Pedro Giesteira Cotovio, David Herron +4

The use of ontologies and knowledge graphs is becoming increasingly widespread in the defence and national security domain. Numerous ontologies have been developed through initiati…

q-bio.BM2026

Reinforcement-guided generative protein language models enable de novo design of highly diverse AAV capsids

Lucas Ferraz, Ana F. Rodrigues, Pedro Giesteira Cotovio +5

Adeno-associated viral (AAV) vectors are widely used delivery platforms in gene therapy, and the design of improved capsids is key to expanding their therapeutic potential. A centr…

q-bio.QM2026★ 1 cited

Exploring the limits of pre-trained embeddings in machine-guided protein design: a case study on predicting AAV vector viability

Ana F. Rodrigues, Lucas Ferraz, Laura Balbi +2

Effective representations of protein sequences are widely recognized as a cornerstone of machine learning-based protein design. Yet, protein bioengineering poses unique challenges…

cs.AI2023

What can knowledge graph alignment gain with Neuro-Symbolic learning approaches?

Pedro Giesteira Cotovio, Ernesto Jimenez-Ruiz, Catia Pesquita

Knowledge Graphs (KG) are the backbone of many data-intensive applications since they can represent data coupled with its meaning and context. Aligning KGs across different domains…