3 papers
physics.bio-ph2026
Protein eXplosion Imaging (PXI): Protein Structures from Laser-Driven Explosions
Alfredo Bellisario, Tomas André, Carl Caleman +1
We investigate the structural information retained in the distribution of explosion ion trajectories from proteins subjected to strong ionization. Using molecular-dynamics simulati…
physics.chem-ph2026
Orientation Reconstruction of Proteins using Coulomb Explosions
Tomas André, Alfredo Bellisario, Nicusor Timneanu +1
We solve the orientation recovery of a tumbling protein in the gas phase from single-event measurements of the spatial positions of its ions after an X-ray laser induced explosion.…
physics.chem-ph2024
Partial Orientation Retrieval of Proteins From Coulomb Explosions
Tomas André, Emiliano De Santis, Nicusor Timneanu +1
Single Particle Imaging techniques at X-ray lasers have made significant strides, yet the challenge of determining the orientation of freely rotating molecules during delivery rema…