4 papers
Dead Zones Enable Flexible Phase Organization in Coupled Oscillators
Naghmeh Akhavan, Ruby Kim
Coupled oscillator networks underlie many biological systems, from cardiac cycles to circadian rhythms. Phase-reduced models such as the Kuramoto model have been widely used to stu…
Cell Migration Boundary Motion in Drosophila Egg Chambers: A Combined Phase Field and Chemoattractant Model
Naghmeh Akhavan, Alexander George, Michelle Starz-Gaiano +1
In the Drosophila melanogaster egg chamber, the collective migration of border cells toward the oocyte is guided by spatial gradients of chemoattractants. While cellular responses…
A Data-Driven Measure of REM Sleep Propensity for Human and Rodent Sleep
Naghmeh Akhavan, Alexander G. Ginsberg, Madelyn E. C. Cruz +6
Mammalian sleep is characterized by multiple alternations between episodes of rapid-eye-movement sleep (REMS) and non-REM sleep (NREMS). While the mechanisms governing the timing o…
Phase-Field Modeling of Border Cell Cluster Migration in Drosophila
Naghmeh Akhavan, Alexander George, Michelle Starz-Gaiano +1
Collective cell migration is a fundamental biological process that drives events such as embryonic development, wound healing, and cancer metastasis. In this study, we develop a bi…