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A network-level transport model of tau progression in the Alzheimer's brain
Veronica Tora, Justin Torok, Michiel Bertsch +1
One of the hallmarks of Alzheimer's disease (AD) is the accumulation and spread of toxic aggregates of tau protein. The progression of AD tau pathology is thought to be highly ster…
math.AP2022
The role of beta-amyloid and tau proteins in Alzheimer's disease: a mathematical model on graph
Michiel Bertsch, Bruno Franchi, Maria Carla Tesi +1
In this Note we study a mathematical model for the progression of Alzheimer's Disease in the human brain. The novelty of our approach consists in the representation of the brain as…