activity
20172026
most citedA Flexible Approach for Predictive Biomarker Discovery

12 citations · 29 across the 8 of their papers we have counts for

collaborators

8 papers

stat.ME2026

Causal inference via propensity scores for case-control studies

Yan Liu, Anita Koushik, Philippe Boileau +5

Propensity score methods for causal inference are increasingly being used in cohort and experimental designs, but their development and uptake in outcome-dependent sampling schemes…

stat.ME2026

Identifying and Estimating Causal Direct Effects Under Unmeasured Confounding

Philippe Boileau, Nima S. Hejazi, Ivana Malenica +3

Causal mediation analysis provides techniques for defining and estimating effects that may be endowed with mechanistic interpretations. With many scientific investigations seeking…

stat.ME2025

Assumption-Lean Differential Variance Inference for Heterogeneous Treatment Effect Detection

Philippe A. Boileau, Hani Zaki, Gabriele Lileikyte +3

The conditional average treatment effect (CATE) is frequently estimated in clinical studies to refute a homogeneous treatment effect hypothesis. Under this regime, all patients mak…

stat.ME2023

Guidance on Individualized Treatment Rule Estimation in High Dimensions

Philippe Boileau, Ning Leng, Sandrine Dudoit

Individualized treatment rules, cornerstones of precision medicine, inform patient treatment decisions with the goal of optimizing patient outcomes. These rules are generally unkno…

stat.ME2023★ 5 cited

A nonparametric framework for treatment effect modifier discovery in high dimensions

Philippe Boileau, Ning Leng, Nima S. Hejazi +2

Heterogeneous treatment effects are driven by treatment effect modifiers, pre-treatment covariates that modify the effect of a treatment on an outcome. Current approaches for uncov…

stat.ME2022★ 12 cited

A Flexible Approach for Predictive Biomarker Discovery

Philippe Boileau, Nina Ting Qi, Mark J. van der Laan +2

An endeavor central to precision medicine is predictive biomarker discovery; they define patient subpopulations which stand to benefit most, or least, from a given treatment. The i…

stat.ME2021★ 6 cited

Cross-Validated Loss-Based Covariance Matrix Estimator Selection in High Dimensions

Philippe Boileau, Nima S. Hejazi, Mark J. van der Laan +1

The covariance matrix plays a fundamental role in many modern exploratory and inferential statistical procedures, including dimensionality reduction, hypothesis testing, and regres…

stat.ME2017★ 6 cited

A generalization of moderated statistics to data adaptive semiparametric estimation in high-dimensional biology

Nima S. Hejazi, Philippe Boileau, Mark J. van der Laan +1

The widespread availability of high-dimensional biological data has made the simultaneous screening of many biological characteristics a central problem in computational biology an…