4 papers
Generalized win fraction regression for composite survival endpoints
Zhiqiang Cao, Xi Fang, Fan Li
We propose a generalized win fraction regression framework for prioritized composite survival outcomes. The framework models the conditional win fraction through a chosen link func…
Sample size determination for win statistics in cluster-randomized trials
Xi Fang, Zhiqiang Cao, Fan Li
Composite endpoints are increasingly used in clinical trials to capture treatment effects across multiple or hierarchically ordered outcomes. Although inference procedures based on…
Covariate-adjusted win statistics in randomized clinical trials with ordinal outcomes
Zhiqiang Cao, Scott Zuo, Mary Ryan Baumann +4
Ordinal outcomes are common in clinical settings where they often represent increasing levels of disease progression or different levels of functional impairment. In this article,…
Assessing mediation in cross-sectional stepped wedge cluster randomized trials
Zhiqiang Cao, Fan Li
Mediation analysis has been comprehensively studied for independent data but relatively little work has been done for correlated data, especially for the increasingly adopted stepp…