3 papers
cs.AI2026
MolDA: Molecular Understanding and Generation via Large Language Diffusion Model
Seohyeon Shin, HanJun Choi, Jun-Hyung Park +2
Large Language Models (LLMs) have significantly advanced molecular discovery, but existing multimodal molecular architectures fundamentally rely on autoregressive (AR) backbones. T…
q-bio.MN2023
Noise robustness and metabolic load determine the principles of central dogma regulation
Teresa W. Lo, Han James Choi, Dean Huang +1
The processes of gene expression are inherently stochastic, even for essential genes required for growth. How does the cell maximize fitness in light of noise? To answer this quest…
physics.bio-ph2023
The one-message-per-cell-cycle rule: A conserved minimum transcription level for essential genes
Teresa W. Lo, Han Kyou James Choi, Dean Huang +1
The inherent stochasticity of cellular processes leads to significant cell-to-cell variation in protein abundance. Although this noise has already been characterized and modeled, i…