9 citations · 10 across the 4 of their papers we have counts for
4 papers
Quantifying the Spatiotemporal Dynamics of Engineered Cardiac Microbundles
Hiba Kobeissi, Samuel J. DePalma, Javiera Jilberto +3
Brightfield time-lapse imaging is widely used in cardiac tissue engineering, yet the absence of standardized, interpretable analytical frameworks limits reproducibility and cross-p…
MicroBundleCompute: Automated segmentation, tracking, and analysis of subdomain deformation in cardiac microbundles
Hiba Kobeissi, Javiera Jilberto, M. Çağatay Karakan +9
Advancing human induced pluripotent stem cell derived cardiomyocyte (hiPSC-CM) technology will lead to significant progress ranging from disease modeling, to drug discovery, to reg…
A Data-Driven Computational Model for Engineered Cardiac Microtissues
Javiera Jilberto, Samuel J. DePalma, Jason Lo +5
Engineered heart tissues (EHTs) present a potential solution to some of the current challenges in the treatment of heart disease; however, the development of mature, adult-like car…
Remodeling of Fibrous Extracellular Matrices by Contractile Cells: Predictions from Discrete Fiber Network Simulations
Abhilash Nair, Brendon M. Baker, Britta Trappmann +2
Contractile forces exerted on the surrounding extracellular matrix (ECM) lead to the alignment and stretching of constituent fibers within the vicinity of cells. As a consequence,…