3 papers
q-bio.QM2026
Quantifying the Spatiotemporal Dynamics of Engineered Cardiac Microbundles
Hiba Kobeissi, Samuel J. DePalma, Javiera Jilberto +3
Brightfield time-lapse imaging is widely used in cardiac tissue engineering, yet the absence of standardized, interpretable analytical frameworks limits reproducibility and cross-p…
q-bio.QM2023
MicroBundleCompute: Automated segmentation, tracking, and analysis of subdomain deformation in cardiac microbundles
Hiba Kobeissi, Javiera Jilberto, M. Çağatay Karakan +9
Advancing human induced pluripotent stem cell derived cardiomyocyte (hiPSC-CM) technology will lead to significant progress ranging from disease modeling, to drug discovery, to reg…
q-bio.TO2023
A Data-Driven Computational Model for Engineered Cardiac Microtissues
Javiera Jilberto, Samuel J. DePalma, Jason Lo +5
Engineered heart tissues (EHTs) present a potential solution to some of the current challenges in the treatment of heart disease; however, the development of mature, adult-like car…