24 citations · 24 across the 3 of their papers we have counts for
3 papers
math.DS2026
Best Practices on QSP Model Reporting for Regulatory Use: perspectives from ISoP QSP SIG Working Group
Susana Zaph, Blerta Shtylla, Steve Chang +12
Quantitative systems pharmacology (QSP) models are increasingly applied to inform decision making across drug development and to support regulatory interactions within model inform…
q-bio.CB2015★ 24 cited
A Model for Direction Sensing in Dictyostelium Discoideum: Ras Activity and Symmetry Breaking Driven by a Gbetagamma- Mediated, Galpha2-Ric8 -- Dependent Signal Transduction Network
Yougan Cheng, Hans Othmer
Many eukaryotic cells, including Dictyostelium discoideum (Dicty), neutrophils and other cells of the immune system, can detect and reliably orient themselves in chemoattractant gr…
q-bio.QM2014
Energy Demand and Metabolite Partitioning in Spatially Lumped and Distributed Models of Neuron-Astrocyte Complex
Daniela Calvetti, Yougan Cheng, Erkki Somersalo
The degrees of freedom of multi-compartment mathematical models for energy metabolism of a neuron-astrocyte complex may offer a key to understand the different ways in which the en…