108 citations · 372 across the 13 of their papers we have counts for
13 papers
Binding and segregation of proteins in membrane adhesion: Theory, modelling, and simulations
Thomas R. Weikl, Jinglei Hu, Batuhan Kav +1
The adhesion of biomembranes is mediated by the binding of membrane-anchored receptor and ligand proteins. The proteins can only bind if the separation between apposing membranes i…
Stiffness of the C-terminal disordered linker affects the geometry of the active site in endoglucanase Cel8A
Bartosz Rozycki, Marek Cieplak
Cellulosomes are complex multi-enzyme machineries which efficiently degrade plant cell-wall polysaccharides. The multiple domains of the cellulosome proteins are often tethered tog…
Unbinding and unfolding of adhesion protein complexes through stretching: Interplay between shear and tensile mechanical clamps
Bartosz Rozycki, Lukasz Mioduszewski, Marek Cieplak
Using coarse-grained molecular dynamics simulations, we analyze mechanically induced dissociation and unfolding of the protein complex CD48-2B4. This heterodimer is an indispensabl…
Citrate synthase proteins in extremophilic organisms: Studies within a structure-based model
Bartosz Rozycki, Marek Cieplak
We study four citrate synthase homodimeric proteins within a structure-based coarse-grained model. Two of these proteins come from thermophilic bacteria, one from a cryophilic bact…
Segregation of receptor-ligand complexes in cell adhesion zones: Phase diagrams and role of thermal membrane roughness
Bartosz Rozycki, Reinhard Lipowsky, Thomas R. Weikl
The adhesion zone of immune cells, the 'immunological synapse', exhibits characteristic domains of receptor-ligand complexes. The domain formation is likely caused by a length diff…
Adhesion of surfaces via particle adsorption: Exact results for a lattice of fluid columns
Bartosz Rozycki, Reinhard Lipowsky, Thomas R. Weikl
We present here exact results for a one-dimensional gas, or fluid, of hard-sphere particles with attractive boundaries. The particles, which can exchange with a bulk reservoir, med…