4 papers
A Quasi-Regression Method for the Mediation Analysis of Zero-Inflated Single-Cell Data
Seungjun Ahn, Donald Porchia, Panos Roussos +3
Recent advances in single-cell technologies have advanced our understanding of gene regulation and cellular heterogeneity at single-cell resolution. Single-cell data contain both g…
Kernel-based multi-marker tests of association based on the accelerated failure time model
Chenxi Li, Di Wu, Qing Lu
Kernel-based multi-marker tests for survival outcomes use primarily the Cox model to adjust for covariates. The proportional hazards assumption made by the Cox model could be unrea…
An Association Test Based on Kernel-Based Neural Networks for Complex Genetic Association Analysis
Tingting Hou, Chang Jiang, Qing Lu
The advent of artificial intelligence, especially the progress of deep neural networks, is expected to revolutionize genetic research and offer unprecedented potential to decode th…
A Kernel-Based Neural Network Test for High-dimensional Sequencing Data Analysis
Tingting Hou, Chang Jiang, Qing Lu
The recent development of artificial intelligence (AI) technology, especially the advance of deep neural network (DNN) technology, has revolutionized many fields. While DNN plays a…