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q-bio.PE2025
Algorithms for Reconstructing B Cell Lineages in the Presence of Context-Dependent Somatic Hypermutation
Yongkang Li, Kevin J. Wiehe, Scott C. Schmidler
We introduce a method for approximating posterior probabilities of phylogenetic trees and reconstructing ancestral sequences under models of sequence evolution with site-dependence…
q-bio.PE2025
Posterior bounds on divergence time of two sequences under dependent-site evolutionary models
Joseph Mathews, Scott C. Schmidler
Let $\x$ and $\y$ be two length DNA sequences, and suppose we would like to estimate the divergence time . Under suitable conditions, a well-known simple but crude estimate…