3 papers
cs.AI2026
Improving Interoperability among Defence and National Security Ontologies: Analysis and Evaluation Tasks
Jonathon Dilworth, Pedro Giesteira Cotovio, David Herron +4
The use of ontologies and knowledge graphs is becoming increasingly widespread in the defence and national security domain. Numerous ontologies have been developed through initiati…
q-bio.BM2026
Reinforcement-guided generative protein language models enable de novo design of highly diverse AAV capsids
Lucas Ferraz, Ana F. Rodrigues, Pedro Giesteira Cotovio +5
Adeno-associated viral (AAV) vectors are widely used delivery platforms in gene therapy, and the design of improved capsids is key to expanding their therapeutic potential. A centr…
q-bio.QM2026
Exploring the limits of pre-trained embeddings in machine-guided protein design: a case study on predicting AAV vector viability
Ana F. Rodrigues, Lucas Ferraz, Laura Balbi +2
Effective representations of protein sequences are widely recognized as a cornerstone of machine learning-based protein design. Yet, protein bioengineering poses unique challenges…