4 papers · 1 filter
The first major transition: Origin of life from a multilevel selection perspective
Eugene V Koonin
The origin of life is the first, arguably, the most important and also the most enigmatic major transition in evolution (MTE). As all MTE, the transition at the origin of life can…
The Emergence of Life in the Light of Evolution
Betül Kaçar, Tom A. Williams, Laura Eme +14
The origin of life is often framed primarily as a chemical problem, yet life s defining feature is evolution. Advances in geochemistry, prebiotic chemistry and molecular biology ha…
A generative model for bipartite gene-sharing networks
Jaime Iranzo, Pedro Jódar, Eugene V. Koonin +2
Gene-sharing networks provide a powerful framework to study the evolution of viruses and mobile genetic elements. These bipartite networks, which link genes to the genomes that con…
The selfish ribosome
Mart Krupovic, Eugene V. Koonin
The ribosome is responsible for protein synthesis in all cells, and is the largest energy consumer in the cell. We propose that the ribosome originated as a mutualistic symbiont of…