3 papers
physics.optics2026
Sub-micromolar imaging of intrinsic chromophores by two-photon photothermal microscopy captures mitochondrial response to chemotherapy
Nathaniel Hai, Chinmayee Vallabh Prabhu Dessai, Dingcheng Sun +4
Intracellular chromophores (e.g., NADH and FAD) play a central role in regulation of cellular metabolism. Though autofluorescence has been extensively used for label-free mapping o…
physics.bio-ph2026
Label-free Imaging of Single-Biomolecule Structure and Interaction by Stimulated Raman Photothermal Encoded Scattering
Pin-Tian Lyu, Yifan Zhu, Qing Xia +8
Current single molecule methods either rely on fluorescence or lack chemical information. Here we report stimulated Raman photothermal encoded scattering (SRPSCAT) microscopy for q…
physics.optics2025
Transfer-Function Approach to Substrate-Enhanced Diffraction Tomography
Tongyu Li, Yi Shen, Dashan Dong +4
Forward and backward scattering provide complementary volumetric and interfacial information, yet conventional three-dimensional (3D) imaging typically accesses only one. In this L…