5 papers · 1 filter
Individualizing Glioma Radiotherapy Planning by Optimization of Data and Physics-Informed Discrete Loss
Michal Balcerak, Jonas Weidner, Petr Karnakov +8
Brain tumor growth is unique to each glioma patient and extends beyond what is visible in imaging scans, infiltrating surrounding brain tissue. Understanding these hidden patient-s…
A Lightweight Optimization Framework for Estimating 3D Brain Tumor Infiltration
Jonas Weidner, Michal Balcerak, Ivan Ezhov +6
Glioblastoma, the most aggressive primary brain tumor, poses a severe clinical challenge due to its diffuse microscopic infiltration, which remains largely undetected on standard M…
From Fiber Tracts to Tumor Spread: Biophysical Modeling of Butterfly Glioma Growth Using Diffusion Tensor Imaging
Jonas Weidner, Ivan Ezhov, Michal Balcerak +5
Butterfly tumors are a distinct class of gliomas that span the corpus callosum, producing a characteristic butterfly-shaped appearance on MRI. The distinctive growth pattern of the…
Redefining spectral unmixing for in-vivo brain tissue analysis from hyperspectral imaging
Martin Hartenberger, Huzeyfe Ayaz, Fatih Ozlugedik +12
In this paper, we propose a methodology for extracting molecular tumor biomarkers from hyperspectral imaging (HSI), an emerging technology for intraoperative tissue assessment. To…
A Learnable Prior Improves Inverse Tumor Growth Modeling
Jonas Weidner, Ivan Ezhov, Michal Balcerak +11
Biophysical modeling, particularly involving partial differential equations (PDEs), offers significant potential for tailoring disease treatment protocols to individual patients. H…