218 citations · 303 across the 12 of their papers we have counts for
6 papers · 1 filter
Closed-Form Information Capacity of Canonical Signaling Models
Michał Komorowski
We employ a unified framework for computing the information capacity of biological signaling systems using Fisher Information. By deriving closed-form or easily computable informat…
Information-theoretic analysis of multivariate single - cell signaling responses using SLEMI
Tomasz Jetka, Tomasz Winarski, Karol Nienaltowski +2
Mathematical methods of information theory constitute essential tools to describe how stimuli are encoded in activities of signaling effectors. Exploring the information-theoretic…
StochDecomp - Matlab package for noise decomposition in stochastic biochemical systems
Tomasz Jetka, Agata Charzynska, Anna Gambin +2
Stochasticity is an indispensable aspect of biochemical processes at the cellular level. Studies on how the noise enters and propagates in biochemical systems provided us with nont…
Functional redundancy in the NF-κB signalling pathway
Michał Włodarczyk, Tomasz Lipniacki, Michał Komorowski
The ability to represent intracellular biochemical dynamics via deterministic and stochastic modelling is one of the crucial components to move biological sciences in the observe-p…
Decomposing Noise in Biochemical Signalling Systems Highlights the Role of Protein Degradation
Michal Komorowski, Jacek Miekisz, Michael P. H. Stumpf
The phenomena of stochasticity in biochemical processes have been intriguing life scientists for the past few decades. We now know that living cells take advantage of stochasticity…
Bayesian inference of biochemical kinetic parameters using the linear noise approximation
Michal Komorowski, Barbel Finkenstadt, Claire V. Harper +1
Fluorescent and luminescent gene reporters allow us to dynamically quantify changes in molecular species concentration over time on the single cell level. The mathematical modeling…