3 papers
stat.ME2026
Bayesian Mediation Analysis for Individualized Treatment Rules
Emmanuel M. Rockwell, Patrick J. Smith, Michael R. Kosorok +1
The value of an individualized treatment rule (ITR), defined as the expected outcome under treatment assignment according to the rule, is useful for assessing average clinical bene…
stat.OT2026
The Fidelity and Feedback Traps: The Case for Health Digital Twins as Modular Evolving Causal Systems
Nikki L. B. Freeman, Yating Zou, Kyungbok Lee +3
Digital twins for health may be used to compare treatments, project patient trajectories, and support clinical decisions. While related to mechanical digital twins, those initially…
stat.ME2026
A Review of Methods and Practices for Missing Data in Sequential Multiple Assignment Randomized Trials (SMARTs): An Ancillary Study of a Scoping Review
Nikki L. B. Freeman, Chenyao Yu, Margaret Hoch +5
Background: Missing data poses an acute threat to sequential multiple assignment randomized trial (SMART) analyses because of the sequential treatment structure and response-depend…