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physics.med-ph2026
Addressing respiratory gating latency for accurate pulse delivery in preclinical electron FLASH irradiation on a clinical linear accelerator
Rakesh Manjappa, Jinghui Wang, Stavros Melemenidis +15
Background: Clinical linear accelerators are an accessible platform for preclinical research on the biological effects of ultra rapid electron irradiation (FLASH). However, they ar…
physics.med-ph2026
Ultra-Sharp Upright Photon Radiotherapy via Low Energy Extended Distance: An Alternative to FLASH for high flux Sources
Lloyd E Kamole Ghomsi, Clinton Gibson, Veng-Jean Heng +2
Standard 6 megavolt (MV) radiotherapy is limited by source size and secondary electron range to minimum radiological penumbra widths of ~2-3 mm. This study investigates sharper bea…
physics.med-ph2023
Dosimetric calibration of an anatomically specific ultra-high dose rate electron irradiation platform for preclinical FLASH radiobiology experiments
Jinghui Wang, Stavros Melemenidis, Rakesh Manjappa +16
We characterized the dosimetric properties of a clinical linear accelerator configured to deliver ultra-high dose rate (UHDR) irradiation to mice and cell-culture FLASH radiobiolog…