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stat.ME2026
BOOST: Power-Optimal Strong-FWER Testing for Block-Structured Multiplicity
Prasanjit Dubey, Xiaoming Huo
Structured multiple-testing problems (gatekeeping trials, dose-finding, multi-tissue eQTL mapping, bundled-challenger A/B experiments) organize hypotheses into design-imposed block…
stat.ME2026
Optimal multiple testing under family-wise error control: elementary symmetric polynomials and a scalable algorithm
Prasanjit Dubey, Xiaoming Huo
Family-wise error rate control is essential when even one false rejection is costly, but distribution-free procedures do not exploit information in a specified alternative model. E…
stat.ME2025
Most Powerful Test with Exact Family-Wise Error Rate Control: Necessary Conditions and a Path to Fast Computing
Prasanjit Dubey, Xiaoming Huo
Identifying the most powerful test in multiple hypothesis testing under strong family-wise error rate (FWER) control is a fundamental problem in statistical methodology. State-of-t…